Question How do levels of neurofilament light in cerebrospinal fluid (cNfL) compare between neurological conditions and with healthy controls? Findings Among 10 059 individuals in this systematic review and meta-analysis, cNfL was elevated in most neurological...
During the past century, human life expectancy has nearly doubled globally, increasing by more years than it did in all previous millennia combined. Today, 617 million people are 65 years old or older; by 2050, the number will reach 1.6 billion — nearly 20% of the...
There's no cure, but scientists say this drug could help slow the rate at which the disease progresses. Read more on BBC
A special Congrats to Sara Godina & Nemin Chen for successfully passing their prelims 👏🎊
Question Is a mindset of optimism associated with a lower risk of cardiovascular events and all-cause mortality? Findings In this meta-analysis of 15 studies including 229 391 individuals, optimism was associated with a lower risk of cardiovascular events and...
Blood-based biomarkers have the potential to revolutionize clinical practice and clinical trials in Alzheimer disease (AD). However, to date, this “holy grail” opportunity has not been realized owing to a broad range of issues, including the lack of a clearly defined...
